Are there any nutrients that help PS work more effectively?
Acetyl-L-carnitine, vitamins C and E, B vitamins, magnesium, selenium, and NADH all increase the effectiveness of PS.

How to Take PS
As with any brain-energizing nutrient, PS is best avoided near bedtime as it may prevent sleep. It is best taken before or with breakfast and lunch. If you are taking PS to treat any medical condition, or are taking medications, especially psychotropic medications, it is advisable to take PS with the guidance of your health care practitioner. PS is derived from soy, and is suitable for vegetarians.